Pingie: HTTP:: The Pros and Cons of APP

HTTP:: The Pros and Cons of APP
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In a number of medical conditions, the amyloid precursor protein (APP) plays a major role. Doctors and researchers have had their eyes set on the molecule for a long time, attempting to figure out whether it has a good effect on the organism, or a bad one. New investigation is beginning to reveal that the influence is both beneficial and harmful, and that a natural balance is necessary, if APP levels are to have no ill effect on the body, PhysOrg reports. “Our work suggests that APP balance is critical for normal neuronal development, connection of synapses, and dendritic spine development, all of which have implications for the extensive synapse loss and cognitive decline seen in Alzheimer's disease,” Georgetown University Medical Center Department of Neuroscience research scientist Hyang-Sook Hoe, PhD, says. The expert is also the author of a new study detailing the finds, presented recently at the 39th annual meeting of the Society for Neuroscience. “One strateg!
y to counteract development of Alzheimer's disease is to maintain balance in APP protein expression in order to prevent production of Abeta,” the scientist adds. Abeta (amyloid beta) is a 39- to 42-amino acid peptide, created through APP proteolysis. It is one of the main components of amyloid plaques, the formations found in the brains of ...
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http://news.softpedia.com/news/The-Pros-and-Cons-of-APP-124634.shtml
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