HTTP:: Gene Controlling Key Neural Process Discovered
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When a new brain develops, there are two key processes that determine its final architecture â" proliferation and differentiation. The former refers to the actual number of cells that provides the basis for neural growth, while the latter refers to the function these materials take, in becoming a certain type of nerve cell. In a new study, experts from the University of North Carolina (UNC) School of Medicine have determined that the two processes are kept in balance by a single gene, known as GSK-3. If proliferation and differentiation are not in balance, then the brain doesn't develop normally. A higher level of proliferation could mean the appearance of tumors, as neural growth processes spiral out of control. Conversely, too much differentiation, without insufficient numbers, means that the brain will never achieve its billion-neuron architecture, which enabled us to take over the world. The UNC team has discovered that this crucial balance in the normal brain is kept !
by the GSK-3 gene, which, in essence, dictates how neural stem cells will populate the brain. âœIt was really quite striking. Without GSK-3, these neural stem cells just keep dividing and dividing and dividing. The entire developing brain fills up with these neural stem cells that never turn into ...
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http://news.softpedia.com/news/Gene-Controlling-Key-Neural-Process-Discovered-123313.shtml
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Monday, October 5, 2009
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