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An international scientific effort, led by experts in the United Kingdom, has uncovered that women carrying two copies of a single, malfunctioning gene are at increased risk of developing ovary cancer at some point in their life. In a paper published in the latest issue of the scientific journal Nature Genetics, they say that more than 17,000 DNA samples from cancer patients were analyzed for the new study. The results were harsh â€" women carrying the two copies were at 40-percent larger risk of getting ovary cancer than those who did not have the modified gene, the BBC News reports. The flaw was identified on chromosome 9, of the 23 pairs humans have. If the error occurred on both chromosomes of the pair, then the chance of cancer increased from its usual ten in 1,000 to about 14 in 1,000 cases. If it appeared on a single chromosome, then the variant gene caused 12 cases in 1,000. Directly responsible for the onset of the disease are “letters†in the human genetic c!
ode known as single nucleotide polymorphisms (SNP). When arranged slightly different than normal, they can cause severe damage to the body by allowing for cancer to form. For the new research, more than 1,810 women with ovarian cancer, and 2,535 without, from all around the United Kingdom, were studied, and had t...
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http://news.softpedia.com/news/Genetic-Fluke-Increases-Ovarian-Cancer-Risk-by-40-Percent-118181.shtml
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