Thursday, October 15, 2009

Pingie: HTTP:: How T Cells Penetrate the Central Nervous System

HTTP:: How T Cells Penetrate the Central Nervous System
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Autoimmune diseases are among the most dangerous kind in the world. They manifest themselves when the body's own immune system begins to attack the central nervous system (CNS), inflicting severe damage, and eventually leading to death. Multiple sclerosis is one good example. Although the barriers that exist between the CNS and other parts of the body seem to be extremely well constructed, a new video shows precisely how T cells, an important part of the immune system, go through these defenses, and start their attacks. In the new investigation, a team of scientists from the University Medical Center Institute for Multiple Sclerosis Research, in Gottingen, Germany, managed to track down the movements of the T cells inside a mouse model, and got a chance to look at how they passed through the barrier surrounding the CNS. The research was led by Alexander Flugel, who is also the director of the Institute, Nature News reports. “There's a question about how immune cells that!
attack the brain get entry because [it] is shielded by the blood-brain barrier,” he says. In order to get the best possible view of how these cells acted, the researchers tagged disease-causing T cells with green fluorescent proteins, and then injected the batch into the veins of rats. They then used infrared lasers, and ...
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http://news.softpedia.com/news/How-T-Cells-Penetrate-the-Central-Nervous-System-124340.shtml
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