Pingie: HTTP:: How Bacteria Repair Their RNA

HTTP:: How Bacteria Repair Their RNA
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Scientists were recently able to determine precisely how bacteria repaired their own RNA. This is the second such mechanism identified in any living thing, with the first having been found some time ago, in the T4 phage, a virus that attacks bacteria. The find was made by a team of scientists from the University of Illinois (UI), led by Biochemistry Professor Raven H. Huang. Details of the investigation appear in two papers, to be published in the top journal Science, and also in the Proceedings of the National Academy of Sciences (PNAS), e! Science News reports. The thing about the new repair system is that it makes the damaged RNA “better than new.” That is to say, before it is “sealed” (so as to avoid future damage), a methyl group is added to the two-prime hydroxyl groups at the cleavage site. This prevents the molecule from being cleaved again in the future, the scientists report. The main class of biomolecules that use this RNA vulnerability consists of ribo!
toxins, which destroy cells by randomly cleaving RNA molecules. This impairs cellular functions, eventually leading to its destruction. “Hen1 is one of three essential enzymes in generating small noncoding RNAs for RNA interference in eukaryotes. We found out that Hen1 homologs exist in bacteria, but bacteria have no RNA interfer...
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http://news.softpedia.com/news/How-Bacteria-Repair-Their-RNA-124129.shtml
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