Pingie: HTTP:: New Stem Cell Gene Splicing Method Created

HTTP:: New Stem Cell Gene Splicing Method Created
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Experts from the Whitehead Institute for Biomedical Research have recently managed to overcome a major obstacle in human embryonic stem cell (ESC) and induced pluripotent stem (iPS) cell research, when they devised a new method of introducing or modifying genes inside them. While this has been relatively easy to do in mice, altering the human genome proved to be infinitely more complicated, and no technique available until now had such a high success rate as the new one. The experts also authored a new paper detailing the find, published in the August 13th issue of the journal Nature Biotechnology. “It's not clear where this hurdle of genetic manipulation lies; it could be purely technical, but it could also be an inherent difference between human and mouse cells. Other people have genetically manipulated these human cells, but the process has been extremely laborious and extremely time consuming. Using the zinc finger nucleases makes the process very easy,” explains W!
hitehead postdoctoral researcher Dirk Hockemeyer, who is also a first author of the Nature paper. Zinc finger nucleases, the authors say, are a relatively unknown class of proteins, which have the ability to facilitate tempering with, or replacement, of existing genes in the human genome. The new study “is a proof of princi...
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http://news.softpedia.com/news/New-Stem-Cell-Gene-Splicing-Method-Created-119355.shtml

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