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Bioengineering is one of the most promising fields of science today, because it has the ability to transform all organisms into better, more efficient versions of themselves. Genomes are read via high-throughput sequencing at a speed of a few million DNA letters or bases per hour, but, when it comes to tinkering with the sequences, the job suddenly becomes very difficult. Old manipulation techniques have not received upgrades for years, so teams around the world spend countless hours modifying just a subsection of a single gene, before finally moving on to the next one. Now, a new system has the power to change all that, its creators reveal.The Multiplex Automated Genome Engineering (MAGE) programming method, devised at the Harvard Medical School by Professor of Genetics George Church, is touted as having the ability to overcome these obstacles, and to offer a major boost to the sector of synthetic biology. In a proof-of-concept trial, the team behind MAGE managed to use th!
e system in a manner that allowed for the modification of E. coli bacterial colonies in just three days. Colonies are used all the time, to synthesize antibiotics and other drugs, but it usually takes months to years before the correct type is grown from basic bacteria.The new method does i...
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http://news.softpedia.com/news/New-Bacterial-Engineering-Method-Could-Result-in-Higher-Yields-117593.shtml
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